Drugs

Our body likes to stay and keep itself in a state of homeostasis. I think it is best not to mess with this state too much. Or if one does, one should leave enough time for the body to come back to normal.

Moderation is key with drugs of any kind, be it medicine or recreational use. Knowing what the appropriate dosage is, what effects a drug has and what are the consequences of taking the drug is of utmost importance.

Notes

• The drug isn't the issue its our relationship with them.
• The difference between a medicine and a poison is the dose, and the method for finding the right dose varies from person to person.
• Synthetic production has changed the end product and the way it affects the user. It is said that psychosis observed in users of the early 2000's type of ephedrine-sourced meth was typically due to the user being awake for several days, where as modernly produced meth can induce such psychosis within hours of use. This seems to indicate higher neurotoxicity, and the author questions whether it is due increased potency or contamination of product through production.

Links

• PsychonautWiki - Amazing resource.
• Reagent test instructions
• DeepChem - Democratizing Deep-Learning for Drug Discovery, Quantum Chemistry, Materials Science and Biology. (Web) (Predicting Aqueous Solubility - It's Harder Than It Looks)
• Molecular Sets - Benchmarking Platform for Molecular Generation Models.
• Decriminalization 2020 - Drug abuse is a public health issue, not a crime.
• Resource for chemistry knowledge
• TheeHive subreddit - Synthesizing chemicals/drugs.
• BabyBees subreddit - Subreddit for those brand new to the Hive to ask questions and learn, and for experienced bees to answer questions.
• Aldous Huxley Foresaw America’s Pill-Popping Addiction (HN)
• Speeding up drug discovery with advanced machine learning (2020)
• Relay Therapeutics - Clinical-stage precision medicine company transforming the drug discovery process.
• Drug Repurposing Knowledge Graph (DRKG) - Comprehensive biological knowledge graph relating genes, compounds, diseases, biological processes, side effects and symptoms.
• Debunking Crystal Meth Myths | The War on Drugs (2020)
• Know Your Amphetamines (2021)
• What are your top 5 favorite drugs? (2021)
• How Antidepressants Work, At Last? (2021)
• A Look Down Track B (2021) - Do antidepressants bind to TrkB receptors directly?
• What drugs aren’t as bad for you as people make them out to be? (2021)
• Tripby - Understand your substances, their effects, dosage and duration. (Code)
• What do you guys think about the future of drugs? (2021)
• Drugs Reddit Wiki
• Documentary about benzodiazepine withdrawal syndrome
• What is the closest thing to a "pure-euphoriant" out there? (2021)
• Drugs Reddit Knowledge Base
• Drugs Reddit Wiki
• Drug Users Use a Lot of Drugs (2021) (HN)
• Open Targets Platform - Comprehensive tool that supports systematic identification and prioritisation of potential therapeutic drug targets. (Code)
• From PCP to MXE: a comprehensive review of the non-medical use of dissociative drugs (2014)
• Hamilton Morris and Jason Wallach | Arylcyclohexylamines (2015)
• Drugs and Me - Harm reduction guide to safer drug use.
• You're entitled to use substances however you wish to so long as you're not hurting yourself or anyone.
• Streets of Philadelphia, Kensington Avenue (2021) - Watching it with this song in background is surreal. (Tweet)
• 4-Methyl Methcathinone synthesis, Hive Novel Discourse
• 4mmc Synthesis
• The Hive Archive
• What is the longest lasting drug? (2021)
• Smoking, Genetics and Schizophrenia: Evidence for Self Medication (2007) (Reddit)
• Long-term risks of stimulants in humans (2021)
• The main thing about Phenylacetone meth is that there's so much of it (HN)
• Bluelight.org
• What’s the druggiest drug to you? (2021)
• What are your personal favorite drugs in every category? (2021)
• Whats your top 5 drugs guys? (2021)
• What’s the most addictive drug you have tried? And why? (2021)
• TorchDrug - PyTorch-based machine learning toolbox designed for several purposes. (Web)
• Мефедрон - окно в мир психических расстройств (2021)
• ChemicalX - PyTorch based deep learning library for drug-drug interaction, polypharmacy side effect and synergy prediction.
• Dopesick Series
• What drug made you think "holy fuck how is this even possible"? (2022)
• MLDD 2022 - Machine Learning for Drug Discovery Workshop
• What's your drug bucket list? (2022)
• How do you get paper tabs through TSA/on a plane?
• The Uselessness of Phenylephrine (2022) (HN)
• What’s everyone favorite 2 drug combination
• Salvum - Consolidates harm reduction resources in one place. (Code)
• Movies with accurate“drug trip sequences”
• Open Drug Discovery Toolkit (ODDT) - Modular and comprehensive toolkit for use in cheminformatics, molecular modeling etc.
• Isomorphic Labs - Reimagining the entire drug discovery process from first principles with an AI-first approach. (Twitter)
• What's PCP "Angel Dust" Addiction Like? 5 Years Sober
• What are all the natural drugs? (2022)
• Психиатр-Нарколог. Мефедрон, лечение наркозависимых, 12 шагов (2022)
• Lucy - Nicotine for normal people.
• Which drug provide the greatest music enhancement for you? (2022)